Across the DIC spectrum, which presentation is seen in acute DIC but not typically in chronic DIC?

Across the DIC spectrum, which presentation is seen in acute DIC but not typically in chronic DIC?

• A. normal PT
• B. normal aPTT
• C. decreased D-dimer
• D. decreased platelets

Answer: (D)

In DIC, widespread activation of coagulation consumes platelets and coagulation factors. This consumption is rapid in acute DIC, leading to a noticeable drop in platelet count. In chronic DIC, the process is slower and platelet production can keep up, so platelets often stay normal. So a decreased platelet count is seen with acute DIC but not typically in chronic DIC. D-dimer is usually elevated in both states due to fibrin degradation, and PT/aPTT are more likely prolonged in acute DIC due to factor consumption, making normal levels less typical of the acute presentation.

In DIC, widespread activation of coagulation consumes platelets and coagulation factors. This consumption is rapid in acute DIC, leading to a noticeable drop in platelet count. In chronic DIC, the process is slower and platelet production can keep up, so platelets often stay normal. So a decreased platelet count is seen with acute DIC but not typically in chronic DIC. D-dimer is usually elevated in both states due to fibrin degradation, and PT/aPTT are more likely prolonged in acute DIC due to factor consumption, making normal levels less typical of the acute presentation.